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Bet v I allergen is a family of protein allergens. Allergies are hypersensitivity reactions of the immune system to specific substances called allergens (such as pollen, stings, drugs, or food) that, in most people, result in no symptoms. Trees within the order Fagales possess particularly potent allergens, e.g. the prototypical Bet v1, the major white birch (''Betula verrucosa'') pollen antigen. Bet v 1 is the main cause of type I allergies observed in early spring. Type I, or immunoglobulin E-mediated (IgE-mediated) allergies affect 1 in 5 people in Europe and North America. Commonly observed symptoms are hay fever, dermatitis, asthma and, in severe cases, anaphylactic shock. First contact with these allergens results in sensitisation; subsequent contact produces a cross-linking reaction of IgE on mast cells and concomitant release of histamine. The inevitable symptoms of an allergic reaction ensue. ==Categorization== A nomenclature system has been established for antigens (allergens) that cause IgE-mediated atopic allergies in humans.〔(Allergen Nomenclature Subcommittee King T.P., Hoffmann D., Loewenstein H., Marsh D.G., Platts-Mills T.A.E., Thomas W. Bull. World Health Organ. 72:797-806(1994) )〕 This nomenclature system is defined by a designation that is composed of the first three letters of the genus; a space; the first letter of the species name; a space and an Arabic number. In the event that two species names have identical designations, they are discriminated from one another by adding one or more letters (as necessary) to each species designation. The allergens in this family include allergens with the following designations: Bet v 1, Dau c 1, and Pru a 1. Other proteins belonging to this family include the major pollen allergens: * Aln g I from ''Alnus glutinosa'' (Alder); * Api G I from ''Apium graveolens'' (Celery); * Car b I from ''Carpinus betulus'' (European hornbeam); * Cor a I from ''Corylus avellana'' (European hazel); * Mal d I from ''Malus domestica'' (Apple). 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Bet v I allergen」の詳細全文を読む スポンサード リンク
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